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found that the abundance of mitochondrial Asp in T cells in rheumatoid arthritis (RA) was decreased, which inhibited NAD + turnover, resulting in a decrease in NAD + /NADH ratio and a reduction in ADP-ribosylation of proteins which is NAD + dependent

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[142] Identification of liver as an anti-anemia food [edit] During the 1920s, George Whipple discovered that ingesting large amounts of raw liver seemed to most rapidly cure the anemia of blood loss in dogs, and hypothesized that eating liver might treat pernicious anemia